Shane Prejean, MD

Interventional Cardiologist 

Contact Information



225 Dunn Street
Houma, LA 70360
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Dr. Prejean graduated cum laude with a Bachelor of Science degree from Nicholls State University (NSU) in Thibodaux, Louisiana and was inducted into the NSU Hall of Fame. He completed his medical degree at Louisiana State University (LSU) Health Sciences Center in New Orleans. His residency in internal medicine was completed at the LSU Internal Medicine Residency in Baton Rouge, where he was also named chief resident. He completed his fellowship in cardiovascular disease at the University of Alabama at Birmingham (UAB), where he was also named chief fellow. During his fellowship, he was named best teaching fellow and best clinical fellow by the UAB Division of Cardiovascular Disease. Most recently, Dr. Prejean completed an advanced interventional cardiology fellowship in structural heart disease at UAB.

Dr. Prejean is board certified in internal medicine, cardiovascular disease, echocardiography, interventional cardiology, cardiovascular computed tomography and nuclear cardiology. He has a clinical focus on general cardiology, interventional cardiology, coronary artery disease, valvular heart disease, and transcatheter valve therapies. He is a part of the CIS Structural Heart Programs in Houma and Baton Rouge, working closely with cardiovascular surgeons as part of the comprehensive heart team.

Dr. Prejean performs diagnostic and therapeutic procedures including heart catheterization, percutaneous coronary intervention, coronary stent implantation, transcatheter aortic valve replacement (TAVR), transcatheter mitral valve replacement (TMVR), the MitraClip procedure, PFO closure, ASD closure, paravalvular leak closure, and transcatheter therapies for management of pulmonary embolism. He is a member of the American College of Cardiology and the Alpha Omega Alpha Honor Medical Society.


  • Education

    Nicholls State University

    Louisiana State University Health Sciences Center

  • Residency

    LSU Internal Medicine Residency

  • fellowship

    University of Alabama at Birmingham

  • Board certification

    Internal Medicine

    Cardiovascular Disease


    Interventional Cardiology

    Cardiovascular Computed Tomography

    Nuclear Cardiology

  • membership

    American College of Cardiology

    Alpha Omega Alpha Honor Medical Society